LayerZero is an Omnichain Interoperability Protocol designed for lightweight message passing across chains. It provides authentic and guaranteed message delivery with configurable trustlessness, implemented as a set of gas-efficient, non-upgradable smart contracts.

Chainlink is an oracle infrastructure bringing the capital markets onchain and powering the majority of decentralized finance (DeFi). The Chainlink stack provides the essential data, interoperability, compliance, and privacy standards needed to power advanced blockchain use cases for institutional tokenized assets, lending, payments, stablecoins, and more.

Wormhole is a decentralized, universal message-passing protocol that enables developers and users of cross chain applications to leverage the advantages of multiple ecosystems.

Openverse Global is a Layer0 hub network based on blockchain technology. It is based on the existing blockchain technology and proposes the concept of "fully open protocol cross-chain". It will realize "the transmission of value (token/NFT/message) between different blockchains, metaverses and the traditional Internet is as simple as sending email". Openverse has proposed protocol systems such as the "Bitcurrency VRC10 Protocol", "Privcurrency VRC11 Protocol", and "Public Currency Issurance Mechanism, PCIM".

ZetaChain is the foundational, public blockchain that enables omnichain, generic smart contracts, and messaging between any blockchain. ZetaChain envisions and supports a truly fluid, multi-chain crypto ecosystem. These "omnichain" smart contracts can send data and value between connected blockchains, including Ethereum, Polygon, Binance Smart Chain, and eventually, non-smart chains such as Bitcoin and Dogecoin. ZetaChain is built on Cosmos SDK and Tendermint Consensus.

Zeus Network serves as a crucial permissionless layer, harnessing the formidable strengths of both Solana and Bitcoin, that enables dynamic, secure composability, creating a decentralized ecosystem for seamless user engagement and liquidity interaction. Zeus Network is NOT a bridge. Because liquidity providers on each chain do not receive liquidity back on the other chain, the assets provided on each chain are protected by their respective protocols.

PicWe is a decentralized, trustless, omni-chain liquidity infrastructure enabling seamless, cost-efficient trading across multiple blockchains and liquidity pools.

Nomina is a unified trading platform for perpetual futures DEX. Its trading terminal supports users to use pre-built advanced strategies. The project has been upgraded twice, previously known as Omni Network and Rift Finance.

Axelar is a decentralized cross-chain communication network, aiming to level-up interoperability in Web3 by connecting heterogeneous blockchains and enabling asset mobility and program composability in an optimized way for both builders and end-users. The two layers of Axelar are the network and the API above it. At the core of Axelar is a permissionless overlay network that provides Turing-complete cross-chain communication through proof-of-stake and permissionless protocols. On top of the network are APIs and protocols, an application-development layer that developers use to compose across any number of chains. Once integrated, all new interconnected blockchains become interoperable with the application, resulting in limitless network effects.

Hyperlane is the platform for developers building the interchain universe. It provides an on-chain API for sending information between blockchains. Developers can use Hyperlane as an API to easily and securely communicate between blockchains, or they can utilize the Hyperlane SDK and tooling to quickly build interchain applications.

Analog is a completely decentralized layer-0 platform for communicating validated event data with the Proof-of-Time consensus mechanism. At the core of the platform are tesseracts and time nodes that can privately fetch and confirm event data from sovereign chains, allowing different ecosystems to speak the same language. Analog aims to bring trustless, omnichain interoperability, enabling developers to build their applications via a universal protocol and an API. Additionally, Analog is unveiling a novel, superfast PoT protocol that creates verifiable event data on the Timechain, allowing DApp developers to build next-generation event-based applications.

Firefly Bridge is a cross-chain messaging and asset transfer protocol that supports interaction between EVM and non-EVM networks. It uses on-chain contract verification and relay mechanisms to achieve cross-chain operations without custody, and provides a unified interface to simplify the development and use of multi-chain applications.

oooo is a modular omnichain interoperability protocol supporting the Bitcoin ecosystem. Its modular communication protocol architecture ensures the integrity and reliability of data and transactions within the system. This approach resolves blockchain isolation and liquidity fragmentation, boosting capital efficiency and utilization, and ultimately improving the user experience. oooo is pioneering the next evolution in blockchain interoperability by introducing AI Omninet — an intelligent protocol that transforms cross-chain intents into seamless operations.

MAP Protocol is the interoperable layer for the Bitcoin network, built upon ZK light-clients. It is the gateway for Bitcoin ecosystem developers and users and the way for different Bitcoin L2s as well as the Bitcoin ecosystem to become interoperable with EVM & non-EVM ecosystems.

Paloma is a fast, permissionless, Cosmos-SDK blockchain that securely moves messages between any other blockchains. It is designed for developers who want to manage bi-directional messages between chains in a secure and scalable way. Volume provides blockchain messaging software that is secure, scalable, and enables developers to communicate across multiple blockchains at the lowest cost.

Omnity is an omni-chain interoperability protocol built by Octopus Network on the Internet Computer (IC) specially designed to fit the modular blockchain landscape. Omnity addresses challenges like security vulnerability, high cost and latency, and liquidity fragmentation. The ultimate goal of Omnity is to connect thousands of blockchains and facilitate millions of cross-chain transactions per day.

Celer is a blockchain interoperability protocol that provides a one-click user experience for accessing tokens, DeFi, GameFi, NFTs, governance, and more across multiple chains. Developers can use the Celer Inter-chain Message SDK to build inter-chain-native dApps, enabling efficient liquidity utilization, coherent application logic, and shared states.

LI.FI is a bridge aggregation protocol with DEX connectivity and cross-chain data messaging capabilities. All of these functions will be made available on an API/Contract level, and as a widget for other developers to plug directly into their products.

Router Protocol is a cross-chain messaging protocol that uses a mesh network architecture to facilitate communication between different chains. Router offers a suite of products, including its main application, Voyager, a flexible widget, and an SDK called CrossTalk.

TeleSwap is a trustless and universal interoperability protocol that provides developers with an infrastructure to build cross-chain applications. With it, users can transfer any data, such as messages, contract calls, tokens, or NFTs, between blockchains.

Toposis an interoperability protocol that enables public and private blockchains to communicate with each other. Zero-knowledge proofs allow blockchains to prove the validity of their state transitions without revealing private information, such as account addresses and account balances.

Electron Labs is an universal ZK-proof aggregation layer for Ethereum. It uses light clients and zero-knowledge proofs to maintain decentralization. Electron uses UPA underneath to aggregate proofs from multiple source into a single superproof, thus amortizing the cost per use case.

Polymer is the interoperability uub of Ethereum. Polymer provides IBC execution to connected Layer 2s without requiring a native IBC integration, enabling new L2s to permissionlessly connect to the IBC network. Polymer enhances composability between Ethereum rollups while leveraging IBC’s expanding network of applications.

Elk is a peer-to-peer network for cross-chain value transfers and blockchain interoperability. ElkNet, the powerful cross-chain engine at the heart of the network, enables secure and efficient transfers of value and information, reducing friction and asset fragmentation between blockchains. Community projects and developers can also build dynamic multi-chain applications that leverage ElkNet with features such as proxy tokens and cross-chain messaging.

MailZero is a platform that enables Web2 to Web3 interoperability for Stamp2Earn.The underlying layer that MailZero plans to develop hopes to achieve the vision of true interoperability by connecting all chains, whether they are part of the EVM ecosystem, IBC ecosystem, or other ecosystems. Users will no longer be constrained by whether mainstream protocols support certain chains.

Golden Gate (GGX) is a cross-chain infrastructure protocol, which combines public-private key encryption technology with multi-party computing, enhances the security and integrity of transactions on the Golden Gate protocol, and solves the problem of Layer 1 smart contract platforms in the Web3 field. cross-chain communication and asset liquidity issues. Golden Gate aims to provide a next-generation programmable Layer0 with embedded hybrid virtual machines and advanced DeFi orchestration capabilities.

MultichainZ is a cross-chain interoperability protocol acts as a unifying layer, allowing different blockchain networks to seamlessly interact, communicate, and transact with one another.

Hyperbridge is a cryptoeconomic coprocessor for secure, verifiable interoperability powered by consensus and storage proofs. Hyperbridge is the HTTPS of blockchain interoperability, providing developers with onchain and off-chain SDKs for securely sending cross-chain messages (POST requests) and reading on-chain storage (GET requests).

Stripchain is a cross-chain interoperability protocolallows developers to create commands called intents to perform actions like transferring data between blockchains. Based on a system called stripVM, it will enable applications to communicate and coordinate with different protocols.

exSat is a Docking Layer that was built to bridge the gap between Bitcoin’s native layer and a multitude of Layer 2 scaling solutions for the Bitcoin ecosystem. By facilitating direct queries of BTC and ecosystem token balances, exSat enables a seamless flow of assets and information across different networks and Bitcoin Layer 2 scaling solutions.